Applied ICP-MS
This course provides a holistic approach to ICP-MS, from choosing the analytical setup to designing a robust methodology.
In Inductively-Coupled Plasma - Mass Spectrometry (ICP-MS), an inductively coupled plasma (argon gas ionised by an intense electromagnetic field) is used to create ions which are then separated on a charge-to-mass basis and quantified by a mass spectrometer, to as low as ppq detection limits. The intensity of the ion is proportional to the concentration of the sample. Compared to ICP-OES, it gives much lower detection limits.
This course engenders a holistic approach to ICP-MS from the initial choice of analytical set-up through to designing a robust methodology including sample preparation and sample introduction and finishing with calibration. Different applications of ICP-MS will be explored throughout the course. Classroom exercises will explore the knowledge learned through the course.
Learning outcomes
- You will learn the theory behind the technique of Inductively-Coupled Plasma Mass Spectrometry (ICP-MS)
- You will learn the pros and cons of each facet and the required troubleshooting and maintenance of each
- You will learn about the different ICP-MS components, how they are affected by problematical samples and what can be done to reduce plasma and isobaric interferences
- You will gain knowledge in how to optimise a method to build a robust methodology
Who is this course for?
This is an intermediate level course going into reasonable depth on how an ICP-MS instrument works, using, maintaining and troubleshooting it.